Webb1 okt. 2008 · Australian Medicines Handbook section 14.5.3. Anti-thymocyte globulin is indicated for the prophylaxis of renal graft rejection as well as the treatment of steroid-resistant renal transplant rejection. Kidney transplantation is the treatment of choice for most patients with end-stage renal disease. However, 15-35% of transplant recipients … Webb12 jan. 2015 · Anti-thymocyte globulin (ATG) is a polyclonal antibody preparation made by immunizing rabbits, horses or goats with human thymus cells, and purifying the IgG fraction (1). The different preparations have distinct characteristics, such as antibody specificity profiles and clinical efficacy.
Low-dose Anti-thymocyte Globulin Inhibits Human B-cell …
WebbThymoglobuline innehåller natrium. Detta läkemedel innehåller 4 mg natrium per injektionsflaska, motsvarande 0,2 % av WHOs högsta rekommenderat dagligt intag (2 … WebbThymoglobulin is a gamma immune globulin indicated for prophylaxis and treatment of acute rejection in patients receiving a kidney transplant. Thymoglobulin is to be used in conjunction with concomitant immunosuppression. 2 . References . 1. Atgam [package insert]. New York, NY: Pharmacia and Upjohn Co, Division of Pfizer Inc; August 2024. 2. body care huddinge
An avoidable cause of thymoglobulin anaphylaxis Allergy, …
WebbThymoglobulin targets a wide range of T-cell surface antigens as well as natural killer-cell antigens, B-cell antigens, plasma cell antigens, adhesion molecules and chemokine receptors, resulting in profound, long-lasting T-cell depletion. Randomized studies have established the anti-rejection efficacy of Thymoglobulin in kidney transplantation. Webb1 jan. 2013 · This article reviews the available literature on the safety of peripheral administration of ATG preparations, the clinical considerations, and potential economic implications. 1. Background. Antithymocyte globulin (ATG) and antilymphocyte globulin (ALG) preparations are purified gamma-immune globulins that have been used as … Webb23 feb. 2024 · Thymoglobulin® (anti-thymocyte globulin [rabbit]) is a purified pasteurised, gamma immune globulin obtained by immunisation of rabbits with human thymocytes. Anaphylactic allergic reactions to a first injection of thymoglobulin are rare. We report a case of serious anaphylactic reaction occurring after a first intraoperative injection of … body care home 広島