site stats

Thymoglobulin smpc

Webb1 okt. 2008 · Australian Medicines Handbook section 14.5.3. Anti-thymocyte globulin is indicated for the prophylaxis of renal graft rejection as well as the treatment of steroid-resistant renal transplant rejection. Kidney transplantation is the treatment of choice for most patients with end-stage renal disease. However, 15-35% of transplant recipients … Webb12 jan. 2015 · Anti-thymocyte globulin (ATG) is a polyclonal antibody preparation made by immunizing rabbits, horses or goats with human thymus cells, and purifying the IgG fraction (1). The different preparations have distinct characteristics, such as antibody specificity profiles and clinical efficacy.

Low-dose Anti-thymocyte Globulin Inhibits Human B-cell …

WebbThymoglobuline innehåller natrium. Detta läkemedel innehåller 4 mg natrium per injektionsflaska, motsvarande 0,2 % av WHOs högsta rekommenderat dagligt intag (2 … WebbThymoglobulin is a gamma immune globulin indicated for prophylaxis and treatment of acute rejection in patients receiving a kidney transplant. Thymoglobulin is to be used in conjunction with concomitant immunosuppression. 2 . References . 1. Atgam [package insert]. New York, NY: Pharmacia and Upjohn Co, Division of Pfizer Inc; August 2024. 2. body care huddinge https://hutchingspc.com

An avoidable cause of thymoglobulin anaphylaxis Allergy, …

WebbThymoglobulin targets a wide range of T-cell surface antigens as well as natural killer-cell antigens, B-cell antigens, plasma cell antigens, adhesion molecules and chemokine receptors, resulting in profound, long-lasting T-cell depletion. Randomized studies have established the anti-rejection efficacy of Thymoglobulin in kidney transplantation. Webb1 jan. 2013 · This article reviews the available literature on the safety of peripheral administration of ATG preparations, the clinical considerations, and potential economic implications. 1. Background. Antithymocyte globulin (ATG) and antilymphocyte globulin (ALG) preparations are purified gamma-immune globulins that have been used as … Webb23 feb. 2024 · Thymoglobulin® (anti-thymocyte globulin [rabbit]) is a purified pasteurised, gamma immune globulin obtained by immunisation of rabbits with human thymocytes. Anaphylactic allergic reactions to a first injection of thymoglobulin are rare. We report a case of serious anaphylactic reaction occurring after a first intraoperative injection of … body care home 広島

An avoidable cause of thymoglobulin anaphylaxis Allergy, …

Category:Thymoglobulin Versus Basiliximab Induction Therapy in Low-Risk …

Tags:Thymoglobulin smpc

Thymoglobulin smpc

Mechanisms of action of antithymocyte globulin: T-cell depletion …

WebbDocument History Dates Published and Change Reasons Sanofi Genzyme Webb12 jan. 2024 · Excipients : glycine, sodium chlorure, mannitol. Excipients à effet notoire : EEN avec dose seuil : sodium. Présentation. THYMOGLOBULINE 5 mg/ml Pdr sol dil perf Fl. Cip : 3400957028183. Modalités de conservation : Avant ouverture : 2° < t < 8° durant 36 mois (Conserver au réfrigérateur, Ne pas congeler) Commercialisé.

Thymoglobulin smpc

Did you know?

Webb21 apr. 2024 · DESCRIPTION. THYMOGLOBULIN® (anti-thymocyte globulin [rabbit]) is a purified, pasteurized, immunoglobulin G, obtained by immunization of rabbits with human thymocytes. This immunosuppressive product contains cytotoxic antibodies directed against antigens expressed on human T-lymphocytes.. THYMOGLOBULIN is a sterile, … Webb26 nov. 2024 · Thymoglobuline 25 mg powder for solution for infusion Active Ingredient: rabbit anti-human thymocyte immunoglobulin Company: Sanofi Genzyme See contact details ATC code: L04AA04 About Medicine Prescription only medicine Healthcare … Thymoglobulin contains sodium. This medicinal product contains 4 mg sodium … Below is a text only representation of the Patient Information Leaflet (ePIL). The … Health Professionals (SmPC) Patient Leaflet (PIL) Kevzara 150 mg solution for …

Webb29 sep. 2024 · Thymoglobulin is a polyclonal antibody, or an immune globulin, given as an intravenous (IV, into a vein) infusion. Thymoglobulin is used to fight a type of white blood cell called a T-lymphocyte (also called a thymocyte or T-cell). T-lymphocytes are part of your immune system. WebbThymoglobulin is a human prescription drug product labeled by Genzyme Corporation. The generic name of Thymoglobulin is anti-thymocyte globulin (rabbit). The product's dosage form is injection, powder, lyophilized, for solution and is administered via intravenous form. What are the uses for Thymoglobulin?

Webbpatients who have recently received THYMOGLOBULIN (5.7). • THYMOGLOBULIN may interfere with rabbit antibody–based immunoassays and with cross-match or panel … Webb5 apr. 2007 · Thymoglobulin is produced by immunizing pathogen-free New Zealand rabbits with fresh human thymocytes. Thymus fragments are removed from donors undergoing cardiac surgery. Virologic screens are...

Webb15 dec. 2007 · heterogeneous pathways. Thymoglobulin acts as a rapid T-cell depleting agent, primarily through complement-dependent cell lysis in the blood compartment and apoptotic cell death in lymphoid tissues. Although the primary immunosuppressive effect is T-cell depletion, Thymoglobulin has also been shown to modulate cell surface …

Webb8 sep. 2024 · Sanofi’s transplant business mainly consists of Thymoglobulin ® (anti-thymocyte globulin), a polyclonal, anti-human thymocyte antibody preparation that acts as a broad immunosuppressive and immunomodulating agent and Mozobil ® (plerixafor), a hematopoietic stem cell mobilizer. body care home deliveryWebbwww.sahlgrenska.se Doknr. i Barium Dokumentserie Giltigt fr o m Version 21319 su/med 2024-03-08 9 Riktlinje SCT - Thymoglobuline® Innehållsansvarig: Magnus Dahlander, Apotekare Godkänd av: Karin Mellgren, Verksamhetschef, Verksamhet Barncancercentrum (karme5) Denna rutin gäller för: Verksamhet Barncancercentrum Giltig version är … glass window decoration ideasWebb5 apr. 2007 · Thymoglobulin was found strongly to induce apoptosis in vitro against naive, activated B cells and bone marrow resident plasma cells at clinically relevant … glass window film artWebb1 juni 2024 · Thymoglobulin induction therapy showed better outcome with lower rate of acute rejection and borderline change in low-risk patients on contemporary maintenance therapy. A short course (3 days) and relatively low dose (1.5 mg/kg/daily) might be an appropriate dose of thymoglobulin induction for low-risk KT recipients. glass window design for homeWebbThese polyclonal immunoglobulins are IgG preparations from rabbits immunized with human thymocytes (Thymoglobulin) or with the T-acute lymphoblastic leukemia cell line Jurkat (ATG-Fresenius, ATG-F) [ 4 ]. ATG depletes T lymphocytes by induction of apoptosis or complement-dependent lysis. bodycare hugo bossWebbBiverkningar vilka ansågs vara relaterade till Thymoglobulin som rapporterats i kliniska prövningar och efter marknadsföring Blodet och lymfsystemet Mycket vanliga: … glass window film coveringWebbThe purpose of this core SmPC is to provide applicants and regulators with harmonised guidance on the information to be included in the s ummary of product characteristics … glass window designs ideas