WebSzolek,A. et al. (2014) OptiType: precision HLA typing from next-generation sequencing data. Bioinformatics, 30, 3310–3316. About. NeoFuse is a user-friendly pipeline for the prediction of fusion neoantigens from tumor RNA-seq data. Resources. Readme License. GPL-3.0 license Stars. 11 stars Watchers. 7 watching WebJul 14, 2024 · OptiType, Phlat and Polysolver were used to execute HLA typing from WES data, while OptiType, Phlat and seq2hla were utilized for RNA-seq data. As shown in Figure 1, the accuracy of OptiType, Polysolver and Phlat for 4-digit HLA typing of WES data was 99.11%, 95.83% and 93.75%, respectively. Accuracy of OptiType, Phlat and seq2hla from …
HLA--polysolver - 简书
WebJan 8, 2015 · 2)安装. 目前有两种方式来安装 Optitype : 1、基于docker. 如果有docker,那就比较简单了,直接:docker pull fred2/optitype. 然后执行:docker run -v … WebSep 10, 2024 · HLA分型软件总结. HLA分型仍然是现在医学的难题,特别是在现在短读长测序依旧盛行的时代。. 虽然三代测序可有效解决HLA的测序,但现阶段成本较低的依旧是以illumina为首的测序分型。. 临床下在使用的金标准PCR-SBT技术存在分型不唯一的问题。. 主流的两家公司 ... churchman place apts
mskcc/lohhla - Github
WebTumor purity is estimated by ASCAT and Sequenza and is used to derive the clonality measure for the predicted neoantigens. Tumor mutational burden (TMB) is calculated for all variants over the entire read covered genome and for coding variants on read covered exons. HLA class I and class II alleles are predicted with OptiType and HLA-HD. WebNGS-based HLA typing algorithm. Container. Pulls 10K+ Overview Tags. Dockerfile ################################################################# # Dockerfile ... WebJan 8, 2015 · OptiType is a novel HLA genotyping algorithm based on integer linear programming, capable of producing accurate 4-digit HLA genotyping predictions from NGS data by simultaneously selecting all major and minor HLA Class I alleles. Requirements OptiType uses the following software and libraries: Python 2.7 RazerS 3.4 SAMtools 1.2 … churchman roberts dds